Noltrex Vet
Noltrex®Vet is a synthetic 4% polyacrylamide hydrogel (PAAG), used to provide improved joint lubrication. Noltrex®Vet targets a root cause of joint pain by physically reducing friction. Providing long lasting joint lubrication makes Noltrex®Vet an innovative equine therapy, and unlike other products on the market.
Noltrex®Vet coats the cartilage with a protective lubricating layer and reduces friction:
• forms a protective and lubricating layer on the articulating surfaces
• helps restore and maintain healthy joint function
• is gradually removed from the joint without residue
Noltrex®Vet is a synthetic hydrogel comprised primarily of 3-dimensional polyacrylamide (4%) with a high molecular weight of 10 million daltons.
To put that into context, Noltrex®Vet has a molecular weight 3-5 times greater than high molecular weight hyaluronic acids or HA (a large component of normal joint fluid). A higher molecular weight molecule will take longer to break down in the joint of the horse, therefore maintaining effectiveness for longer than a product with a lower molecular weight. Thus, Noltrex®Vet has a substantial advantage over previous equine joint therapies.
Noltrex®Vet substitutes for the lack of lubricating properties of compromised joint fluid to reduce friction and provide physical protection to the cartilage. Protecting sensitive cartilage is critical in order to maintain healthy and pain free joints in horses.
For More Information: https://noltrexvet.com/
Arthramid
Arthramid® Vet is a unique & patented hydrogel, offering an innovative, safe solution for intra-articular therapy in horses to treat both early and late stages of osteoarthritis (OA).
Arthramid® Vet is a biocompatible, non-absorbable, non-pyrogenic, neuro-innocuous injectable polyacrylamide hydrogel for intra-articular injection in animals. Arthramid® Vet consists of approximately 2.5% cross- linked polyacrylamide and 97.5% water for injection.
Studies show 82.5% successful resolution of joint lameness out to 24 months.
Upon injection into joints, Arthramid® Vet adheres to the synovial lining through its ability to exchange water molecules. Over a period of 14 days the gel becomes integrated into the synovial lining and its immediate surrounding tissue of the inner capsule by a combination of cell migration and vessel ingrowth forming a thick, cushion-like membrane consisting of vessel integrated gel covered by a new and hypercellular synovial cell lining.
As a result, Arthramid® Vet has an augmentation effect on both the joint capsule and synovium. It increases the elasticity and tensile strength of the capsule, improving its capacity to transfer load. It is believed that this augmentation and cushioning causes a subsequent reduction in mechanoreceptor activation in the capsule itself. It also causes the formation of a new and hypercellular synovial cell lining, improving the quality of synovial fluid within the joint itself. These actions both help reduce synovitis and its successively deleterious effects.
Unlike other hydrogels Arthramid® Vet becomes fully integrated into the surrounding tissue (rather than encapsulated) and is therefore long lasting. Arthramid® Vet does not elicit a foreign body reaction or harbour infection. Arthramid® Vet is non-pyrogenic, neuro innocuous and contains no heavy metals.
For More Info: https://www.conturavetus.com/product/arthramid-vet/
